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DNA Barcode Generator

FAQ

What is a DNA barcode?

A DNA barcode is a short DNA sequence used as an index or tag to uniquely identify samples in multiplexed experiments such as next-generation sequencing runs.

Why does GC content matter?

Extremely high or low GC content can cause biased amplification or sequencing artefacts. Keeping barcodes within a moderate GC window helps maintain more uniform behavior.

What is Hamming distance?

Hamming distance is the number of positions at which two sequences differ. A higher minimum distance between barcodes makes them more robust to sequencing errors.

What are forbidden motifs?

Forbidden motifs are user-specified subsequences that must not appear in any barcode. They are commonly used to avoid restriction enzyme sites, primer binding sites, and adapters.

Can I download my barcodes?

Yes. On the Home page, once barcodes are generated, you can download them as a CSV file or copy them directly from the table.